Sulforaphane protects against acrolein-induced oxidative stress and inflammatory responses: modulation of Nrf-2 and COX-2 expression

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Sulforaphane protects against acrolein-induced oxidative stress and inflammatory responses: modulation of Nrf-2 and COX-2 expression

INTRODUCTION Acrolein (2-propenal) is a reactive α, β-unsaturated aldehyde which causes a health hazard to humans. The present study focused on determining the protection offered by sulforaphane against acrolein-induced damage in peripheral blood mononuclear cells (PBMC). MATERIAL AND METHODS Acrolein-induced oxidative stress was determined through evaluating the levels of reactive oxygen spe...

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ژورنال

عنوان ژورنال: Archives of Medical Science

سال: 2016

ISSN: 1734-1922

DOI: 10.5114/aoms.2016.59919